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Exploring the potential of oral microbiome biomarkers for colorectal cancer diagnosis and prognosis: A systematic review

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428,429 However, the reported findings are inconsistent, possibly due to selection bias and small study sizes

Ensure that you empty your bowels before inserting the suppository Remove the plastic wrapping from one suppository Insert it gently into the rectum (narrow end first) past the sphincter muscles with your finger (use gloves or our suppository applicator for a cleaner insertion) A suppository needs to go in at least an inch past the rim/muscle of the rectum