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In atherosclerosis, macrophages take up OxLDL to form foam cells and orchestrate inflammatory and reparative responses within vascular lesions, thereby playing a pivotal role in plaque formation and progression (28,34,36)
Desikan SP, Konopleva M, Takahashi K, Lachowiez CA, Loghavi S, MD, Xiao L, Kadia TM, MD, Daver N, MD, Short N, MD, Sasaki K, MD, Borthakur G, MD, Ghayas C Issa GC, Maiti A, Chien KS, Alvarado Y, Montalban-Bravo G, Masarova L, Yilmaz M, Andreeff M , Jabbour E, Garcia-Manero G, Kornblau SM, Ravandi F, Kantarjian H, and DiNardo CD
10.1111/ajd.12290 200 RojiM.SebastianM.LuccaJ
Additionally, the gut microbiota regulates the accumulation of Th17 cells in the lungs by affecting the expression of RegIII (an IL-22-induced antibacterial protein specific to Gram-positive bacteria) and IL-22, thus impacting the immune response during fungal infection (63)
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