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Improved Mood: B12 is known for its role in producing brain chemicals that affect mood, potentially reducing symptoms of depression and anxiety

[7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer

Dimethylaminoethanol pyroglutamate increased choline and acetylcholine extracellular levels in the brains prefrontal cortex in vivo in rat experiments