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While all of the CYP enzymes discussed are involved in statin metabolism, it is likely that genetic variations in enzymes with major metabolism roles have a significant effect on statin disposition

7.6 Anthraquinones: dual modulators of lipogenesis and antioxidant defense Anthraquinones alleviate ALD by suppressing the AMPK/SREBP-1c axis to inhibit de novo lipogenesis and activating the Nrf2/ARE pathway to upregulate antioxidant enzymes such as GST and GR ( Purpurin, an anthraquinone from the roots of Rubia tinctorum L

doi: 10.1111/cea.14046 144 ZhouXSimoninEMJungYSGalliSJNadeauKC

[10] The mechanism of the quantitative assay is mainly based on light absorption