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For example, an engineered Saccharomyces cerevisiae strain produces lactate that exerts dual actions: it inhibits macrophage NLRP3 inflammasome signaling, thereby attenuating inflammation, and serves as a cross-feeding substrate for select commensals, promoting beneficial taxa (e.g., Oscillibacter ) while constraining potentially harmful taxa (e.g., Streptococcus

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Nausea mechanisms peak as the brains chemoreceptor trigger zone responds to increased GLP-1 signaling

substantial data from patients on anticoagulation support the safety of intra-articular injections in patients on antithrombotic therapy [71, 72]