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The addition of semaglutide to this already high-risk group showed further b12 decline, but whether this represents a medication effect, dietary changes from additional appetite suppression, or natural progression of post-surgical deficiency remains unclear

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A population-based study in 3,884 elderly men and women with depressive disorders found that those with vitamin B 12 deficiency were almost 70% more likely to experience depression than those with normal vitamin B 12 status (98)