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For histopathology, fixed liver tissues were dehydrated, embedded in paraffin, and sectioned at 4 m for hematoxylin-eosin (H&E) staining
Summary of Key Amylin-Based Therapies in Development (April 2026) Cagrilintide is a long-acting amylin analogue under investigation for obesity management, and the combination of cagrilintide with semaglutide (CagriSema) has demonstrated superior weight loss and metabolic benefits compared with either agent alone or placebo in recent clinical trials
It modulates specific protein phosphorylation process and intracellular Ca++ concentration through one sperm-specific Ca++ permeable channel (CatSper) in the plasma membrane of the flagellar principal piece, hence it may be beneficial to sperm motility [75,76,77,78,79]
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