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NfL determination NfL was measured with Simoa Human Neurology 4-Plex B assay (N4PB) on a Quanterix SIMOA HD-1 platform, according to manufacturers instructions

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however, to the extent patients were treated with other treatments before SPEVIGO, we question whether it may be appropriate to remove some portion of these charges to avoid inappropriately inflating the average charge per case

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