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A: The unspecified code should only be used temporarily when you have clear evidence of problematic alcohol use but insufficient information to determine if it meets criteria for abuse or dependence

Spiller HA, Winter ML, Weber JA, Krenzelok EP, Anderson DL, Ryan ML

Moreover, e-cigarette use significantly reduces lung function in asthma patients (reduced FEV 1 /FVC ratio and peak expiratory flow (PEF)), and increases the fraction of exhaled nitric oxide (FeNO) and the pH of exhaled breath condensate (EBC) by 3.60 ppb ( p = 0.001) and 0.15 ( p = 0.014), respectively [75]

Many airlines have their own policies banning the use of e-cigarettes on board, and violating these rules can result in fines and other penalties