Microglia populate the CNS during early embryogenesis and primarily function in the phagocytosis of cellular debris, synaptic pruning during neurodevelopment and maturation, and the release of cytokines and growth factors that influence neuronal survival and plasticity (Ginhoux and Prinz, 2015)
Succinate metabolism: a new therapeutic target for myocardial reperfusion injury
This fermentation process generates various byproducts, among which SCFAs are the core pathway connecting gut microbiota and host metabolic interactions (consistent with the previously mentioned mechanism by which proteins and lipids improve mood through the microbiota-SCFAs axis)
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