The GSH concentration rapidly decreased at the end of the fed-batch culture of ZJ000, while no GSH degradation occurred for ZJ1234 and ZJ12345
These findings are consistent with previous studies showing a significantly reduced neuronal A accumulation, enhanced neurogenesis, and promoted cognitive recovery by MSC-Exos [121,122,123]
Similarly, the lack of side products facilitates probe selectivity for thiol residues in targets possessing multiple varying functional groups
While the majority of EC cases are low-grade, early-stage endometrioid EC with favorable prognosis, approximately 1020% fall into the high-risk category, characterized by grade 3 endometrioid tumors (G3EEC), serous ECs (SEC), clear-cell ECs (CCEC), and dedifferentiated carcinosarcomas, all of which exhibit significantly poorer outcomes [3, 4]