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Mast cells increase BBB permeability and allow inflammatory cell infiltrations in the brain after cerebral ischemic brain injury (McKittrick et al., 2015)

Figure 3 Metabolic profiling of mutant and isogenic control iPSC-CMs, and mutated and WT mice To investigate the metabolic consequences of the mutation, we performed a comprehensive metabolomic and lipidomic analysis in mutant and isogenic control CMs, as well as in mutant and WT mouse lower 2/3 heart tissue