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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

The answer lies in the research mentioned above

In a separate set of experiments performed in the other participating laboratory in Turin with the Palo Alto parasite strain, similar data were obtained, showing that the invasion rate of GR-deficient RBCs was as high as that of control RBCs (30% parasitemia at 19 h after inoculation with 6.4% schizonts), and regular development into trophozoites was observed on day 2 (30% parasitemia)

It is also involved in central nervous system (CNS) activities, including the maintenance and development of neurons 117,118