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10.1155/2018/9390810 133 LiuY.DuanC.ChenH.WangC.LiuX.QiuM.et al (2018b)

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Our results show that while on day 7, the signs of inflammation and formation of crusty scab were clearly observed in all the wound tissues treated with the different nanofibrous dressings, these signs almost vanished on day 14 in the tissues treated with the semi or full drug-loaded core-shell nanofibers

When intestinal epithelial cells and immune cells detect bacterial components and metabolites through pattern recognition receptors (e.g., Toll-like receptors, TLRs), they activate NADPH oxidases, resulting in ROS production (O 2 - , H 2 O 2 )