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doi: 10.1111/j.1600-0447.1992.tb10319.x 50 AlvarezBDMoralesCAAmodeoDA

Investigations should be conducted if patients have alarm symptoms (ie, dysphagia, odynophagia, hematemesis, vomiting, or unintentional weight loss), equivocal results on a treatment trial, recurrent symptoms after completion of a treatment trial, or atypical symptoms of sufficient importance to warrant confirmation of GERD