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This is intriguing, as A also undergoes a similar oligmerization process forming a hexameric barrel which also resembles a channel shape in its protofibrilar state, and which has neurotoxic properties, as demonstrated by A 142 (Lendel et al., 2014

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These advanced formulations may enhance Ses ability to reach the thyroid gland more efficiently and potentially reduce toxicity risks by allowing for more controlled release