When given subcutaneously, the product is well-tolerated and non-irritant
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In preclinical and cell culture research, KPV demonstrates suppression of pro-inflammatory cytokines IL-6, IL-1, and TNF- through melanocortin receptor pathway activation
GRAS simply means the FDA agrees that the substance, at intended use levels as a food additive or supplement, is safe based on common use history or expert opinion and does not pose acute toxicity concerns