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Aseptic Non-Touch Technique (ANTT), as recommended by NHS and SPS guidance, is the required standard for preparing injectable medicines

For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia

The trade-off is that thinner needles are slower to draw up medication and slightly more fragile

Semaglutide 2.4 mg once weekly may not work well for certain populations, and the weight loss from bariatric surgery varies greatly (32% of patients with T2DM achieve 5% weight loss with semaglutide 2.4 mg) [112]