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For decades, Marlboro's brand, image, and packaging had done exactly that

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Similar to caffeine, nicotine is both a drug and a stimulant, meaning it can substantially affect the quality of your sleep if consumed in high quantities and too close to bedtime

Since the 1960s, the animal most used in testing the carcinogenicity of tobacco smoke has been the Syrian Golden Hamster due to its resistance to pulmonary infections and the infrequency with which it spontaneously develops pulmonary tumors