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At physiological concentrations, ROS is important to cellular division, but excessive ROS leads to stressed damages to protein, DNA and lipid (Szczepanowska et al., 2012

Severe vitamin B 12 deficiency in a mouse model showed dramatic alterations in the level of DNA methylation in the brain, which might lead to neurologic impairments (103)

BNF recommends hydroxocobalamin rather than cyanocobalamin for vitamin B12 deficiency

9711, otherwise known as the Food and Drug Administration Act of 2009 which provides for the relevant functions, powers and duties of the agency, including the conduct of PMS activities in the monitoring of health products