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However, there were still inconsistencies in the reported literature

Peptides have promising research but lack the large-scale randomized controlled trials needed to establish them as replacements

Biomarkers for endothelial function, insulin sensitivity, intracellular signaling, maintaining DNA integrity , inflammation, metabolic flexibility, mitophagy (recycling old and damaged mitochondria) and cellular senescence (also called "zombie cells" as these cells have lost proper function, harm nearby cells and do not die off) are all improved

The fat-loss, NAD+, and muscle findings people cite are all preclinical too