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As the accumulation of misfolded proteins is a common feature of multiple human neurodegenerative diseases, regulation of autophagy can improve cognitive decline and represent a new therapeutic strategy against neurodegenerative diseases [205]

It isnt clear if these are direct or indirect effects, but the peptide produces a significant pain-relieving effect that is dose dependent

Dihexa, with its combined N-hexanoic-Tyr-Ile-(6) aminohexanoic amide structure, exhibited a significantly extended half-life of 335.5 9.5 min, confirming that both N- and C-terminal modifications are effective strategies for improving metabolic stability [1]

Biochem.Pharmacol