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c-fos is a proto-oncogene that is closely involved in cell growth and differentiation and was also suggested to be involved in smooth muscle cell differentiation (Raimundo et al., 2009)

It is the most common route for musculoskeletal applications because it allows proximal injection near the injury site, which appears to improve local tissue concentration based on animal study findings

Oz M, Al KL, Sadek B, Mahgoub MO (2024) The role of nicotinic acetylcholine receptors in the pathophysiology and pharmacotherapy of autism spectrum disorder: Focus on 7 nicotinic receptors