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For confirmed significant deficiency, a loading protocol with more frequent injections may be recommended initially

Its defined molecular composition makes it suitable for experimental research protocols, in-vitro investigations, and analytical applications carried out within scientific research environments

Vitamin B12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord

Other populations at risk include people who had gastrointestinal surgery (including weight loss surgery) and diseases that affect the gut, such as Crohn's disease or celiac disease