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In the lung ecosystem, virus also plays a pivotal roles in lung diseases, for example, phages could lead to immune-mediated microbial competition [86], opportunistic infection [87], therefore, alterations of lung viral communities could change the bacteriome leading to dysbiosis and disease progression in individuals (e.g., COPD)

Therefore, beginning with the simple fact it may detect the usage of tobacco and smoke and oral marijuana products in different forms

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