the most powerful antioxidant is melatonin not glutathione “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements Melatonin as a mitochondria-targeted antioxidant:

doi: 10.1016/j.jchromb.2016.08.039 193 RamalingamPKoYT

Once calibration had finished, the cell plate was inserted into the analyser, and OCR was determined at basal and mitochondrial stress conditions by triplicate measurement cycles of 0.5 min mixing, 0.5 min waiting and 2 min measuring, carried out at baseline and after each port injection

J Clin Oncol 30(2):134141 Li J et al (2015) Regorafenib plus best supportive care versus placebo plus best supportive care in Asian patients with previously treated metastatic colorectal cancer (CONCUR): a randomised, double-blind, placebo-controlled, phase 3 trial

4.3 Challenges in selective therapeutic target identification The development of effective targeted therapies relies on identifying selective molecular targetsproteins or enzymes with which drugs can interact to exert therapeutic effects