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Minocycline This antibiotic drug has been used due to its additional immunomodulatory and anti-inflammatory properties, with a role in free-radical destruction and salvaging melanocytes from oxidative damage

Activity was monitored by the formation of a fluorescent product (coumarin) generated by a two-step coupled reaction that involved deacetylation of substrate by SIRT-1 followed by secondary release of the fluorophore

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Flos puerariae-semen hoveniae medicinal pair extract ameliorates DSS-induced inflammatory bowel disease through regulating MAPK signaling and modulating gut microbiota composition