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Peptide proponents often stack CJC-1295 with ipamorelin to create the ultimate GH optimization stack. Why people use it: Fans of CJC-1295 use it to optimize their GH pathways, with the ultimate goal of sleeping better, combating weight gain or midlife body changes, improving physical recovery, enhancing skin appearance, and generally promoting anti-aging

This difference was achieved without any change in food intake, suggesting the weight loss came from metabolic changes rather than appetite suppression

But, whether or not to use them should depend on what each patient needs and what the doctor says

Tirzepatide has been associated with modest increases in resting heart rate (mean increase of 24 bpm in clinical trials), though the mechanism is unclear