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Despite the low sequence identities, all cytosolic GSTs share a common fold, which is also largely conserved in mitochondrial GSTs (Fig

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Liver Toxicity: Due to its oral nature, it can put a strain on the liver, potentially leading to liver damage or dysfunction.Hormonal Imbalances: It can suppress natural testosterone production and cause estrogenic effects like water retention and gynecomastia (male breast tissue enlargement).Androgenic Effects: Users may experience side effects such as acne, oily skin, and male-pattern baldness.Cardiovascular Issues: Use can lead to high blood pressure and negative changes in cholesterol levels, increasing the risk of heart disease and stroke