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At the early stage of liver injury, CC-chemokine ligand 2 (CCL2), which is secreted by KCs, triggers circulating Ly6C hi monocytes with CCR2 recruitment into the liver, and the recruited MDMs further secrete pro-inflammatory cytokines and fibrogenic cytokines, accelerating the progression of fibrosis (28)
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*Correspondence: Xavier Kammerscheit, [email protected] Cassier-Chauvat, [email protected] This article was submitted to Microbial Physiology and Metabolism, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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