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Furthermore, siRNA-mediated ATF6 knockdown alleviates macrophage-driven inflammation and fibrosis, highlighting its potential for treating chronic inflammatory disorders (159)

Incidence of Alzheimer's dementia While prevalence refers to existing cases of a disease in a population at a given time, incidence refers to new cases of a disease that develop in a given period in a defined populationfor example, the number of people who develop Alzheimer's dementia during 2025 among U.S