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Strictly on the desensitization question, both belong on the doesnt desensitize list

For starters, a 2021 meta-analysis of eleven clinical studies found that astaxanthin supplementation significantly improved skin moisture and elasticity compared to placebo, but doses above 6mg per day didnt provide additional wrinkle or hydration benefits beyond what 6mg provided.1 So if your primary goal is supporting skin health, a 6mg product like Doctors Best may be all you need

Antioxidant and Cytoprotection Research Research has examined GHK-Cus influence on antioxidant defence systems in cellular models including its activation of superoxide dismutase and other antioxidant enzymes and its cytoprotective effects against oxidative stress-induced cell damage, a key area of interest in ageing biology and cellular protection research

DeNicola, G.M., et al., Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis