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10.24976/Discov.Med.202335177.57 111 ZhangQ.LiJ.LiY.TanG.SunM.ShanY.et al (2022)

Contraindications and Precautions Use of bacteriostatic water should be guided by: The prescribing information of the medication being reconstituted Institutional policies and clinical protocols Professional guidelines (pharmacy boards, nursing associations, medical societies) Individual patient factors and medical history (as determined by the treating healthcare provider) Practitioners should verify that bacteriostatic water is the appropriate diluent for the specific medication being reconstituted, as some medications may require single-dose sterile water or other specific diluents

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The mechanism that lowers postprandial glucose also means the stomach retains contents longer, which is relevant to anyone with pre-existing gastroparesis or significant GI motility disorders, and is a theoretical consideration around procedures requiring an empty stomach