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1b), whose active Fe III center is located in the center of heme (Fe-protoporphyrin IX (Fe-PpIX)), while the axially-ligated tyrosine residue (Tyr 354) can regulate the metal-centered redox potential of heme favoring hydrogen peroxide (H 2 O 2 ) decomposition 2

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62 Fatty fish (like salmon, mackerel, and sardines), walnuts, and flaxseeds are rich in omega-3 fatty acids that may help protect and sustain glutathione levels by reducing oxidative stress