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Metal-responsive transcription factor 1 (MTF-1) plays a crucial role in the cellular response and tolerance to HM stress by activating genes important for HM uptake, transport, and detoxification (Wang et al., 2004)

Protective effect of melatonin against chronic cadmium-induced hepatotoxicity by suppressing oxidative stress, inflammation, and apoptosis in mice

Formononetin ameliorates renal dysfunction, oxidative stress, inflammation, and apoptosis and upregulates Nrf2/HO-1 signaling in a rat model of gentamicin-induced nephrotoxicity

Vitamin C also has the ability to stimulate collagen production, leading to improved skin elasticity and texture