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Zafereo ME , McIver B, Vargas-Salas S, Domnguez JM, Steward DL, Holsinger FC, Kandil E, Williams M, Cruz F, Loyola S, Solar A, Roa JC, Len A, Droppelman N, Lobos M, Arias T, Kong CS, Busaidy N, Grubbs EG, Graham P, Stewart J, Tang A, Wang J, Orloff L, Henrquez M, Lagos M, Osorio M, Schachter D, Franco C, Medina F, Wohllk N, Diaz RE, Veliz J, Horvath E, Tala H, Pineda P, Arroyo P, Vasquez F, Traipe E, Marn L, Miranda G, Bruce E, Bracamonte M, Mena N, Gonzlez HE

Additionally, others may have mutations in their GPX/GST and other genes that put them at risk for low glutathione levels or higher oxidative stress levels

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In obesity, NNMT activity is unusually high in fat cells, which means a lot of nicotinamide gets thrown out before it can be turned into NAD+