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As shown by connected scatterplot in Figure 3 (top-left), the Sucrosomial B12 formulation rapidly raised circulatory vitamin B12 levels above the deficiency threshold, exceeding 300 pg/mL (borderline level) within 24 h (day 1)

For comparison, sulfasalazine (50 mg/kg intraperitoneally, once daily) (moderately effective) or 6--methylprednisolone (1.0 mg/kg intraperitoneally, once daily) (aggravation) was given