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Our findings highlight the relevance of size and concentration in the chronic exposure paradigm

During these stress events, organisms respond within the frame of classic stress reaction schemes, typically involving increased levels of stress hormones, primarily epinephrine (EPI, adrenaline) and cortisol, via activation of the hypothalamic-pituitary-adrenal (HPA) axis, which allows for the rapid mobilization of internal energy resources (McEwen et al., 2007) that produce the classic fight or flight response

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All patients with alcoholic hepatitis should be counseled to completely abstain from alcohol (Class I, level B)