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Our findings indicate the mechanisms by which nicotine influences the neural systems associated with alcohol abuse,providing a foundation for conceptualising strategies aimed at diminishing the link between smoking and later alcohol abuse, said senior author Dr John Dani,of the Baylor College of Medicine in US

The other five CISNET centers that created models are Erasmus Medical Center in the Netherlands, Fred Hutchinson Cancer Research Center in Seattle, Massachusetts General Hospital-Harvard Medical School in Boston, the Pacific Institute for Research and Evaluation in Calverton, Md., and Yale University in New Haven, Conn