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Ca 2+ overload, which is a crucial event in eryptosis, leads to the opening of Ca 2+ -activated K + channel KCa3.1, known as the Gardos channel [90]
Reduced NAD+ availability is associated with impaired cellular energy production, elevated oxidative stress, and accelerated markers of biological aging in animal models
rAAV9-PRMT1 was developed by cloning the target gene PRMT1 into an AAV serotype 9 vector containing the kidney-specific promoter KSPC (GPAAV-KSP0.3k-Mouse_Prmt1-T2A-eGFP-WPRE) (Fig
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