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Recent advancements in research have greatly enhanced our comprehension of BBB dysfunction and furnished us with strategies aiming at restoring the structural and functional BBB in neurodegenerative diseases

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In one clinical trial: GRP was well tolerated in children with ASD Approximately 60% of participants responded positively Improvements were observed in irritability, hyperactivity, and social withdrawal Although further studies are needed, these findings suggest potential interactions between gut peptides and neurological behavior

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