Melanie Avalon: People will talk about with exercise not taking antioxidants because then you won't get this oxidative stress and then you won't get this-- The body rebounding and ultimately dealing better with oxidative stress in the future
147 Overexpression of miR-144-3p could downregulate the GSH/GSSG ratio, increase the levels of ROS, Fe 2+ , and ACSL4, promote ferroptosis and thus reduce the metastasis of osteosarcoma cells, while high expression of ZIB1 plays the opposite role, 147 indicating that miR-144-3p and its downstream ZIB1 are involved in the development and metastasis of osteosarcoma mainly by interfering with iron metabolism and redox homeostasis
doi: 10.1016/j.jep.2023.117089 96 ChyauC-CWangH-FZhangW-JChenC-CHuangS-HChangC-Cet al
Jex AR, Young ND, Sripa J, Hall RS, Scheerlinck J-P, Laha T, Sripa B, Gasser RB