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Furthermore, Ox-LDPE caused more pronounced anxiety-like behaviors compared to LDPE, with oxidized particles producing more severe behavioral impairments (Wang J

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Importantly, in vitro and in vivo , both the blocking of ATG5- and RAB7A-dependent lipid degradation and the enhancement of TPD52-dependent lipid storage prevents RSL3-induced lipid peroxidation and subsequent ferroptosis ( In addition, ferroptosis is also associated with a number of autophagy-related pathways

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