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These agents also influence the activation of Cu/Zn-containing superoxide dismutase, an enzyme involved in scavenging ROS in hypertensive conditions [214]

In addition, the increase in proinflammatory cytokines leads to the formation of fibrin amyloid microclot resistant to fibrinolysis, either by increased production of serum amyloid A (SAA) or by the release of -amyloid (A) peptide by platelets, resulting in capillary obstruction (156159)

Additionally, they decreased levels of granulocyte-macrophage colony-stimulating factor and IL-6 by suppressing the signal transducer and activator of the transcription signaling pathway

Phthalates have endocrine-disrupting properties and are harmful to human health [433]