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Composition The compositions of co-formulations 25 to 32 are shown in table 28 Table 28 Compositions of citrate-buffered cagrilintide and semaglutide co- formulations containing HP-B-CD excipients of varying hydroxypropyl molar substitution degree 1 MS: molar substitution, corresponds to hydroxy propyls per glucose unit Preparation process Formulations were prepared as described in example 1

Draw air into the syringe: Draw back the plunger to fill the syringe with air up to the dose that youll be injecting

Retatrutide, like most peptides, degrades when exposed to improper conditions

Timeline expectations based on mechanisms: Gene expression changes (GHK-Cu) occur within days but take weeks translating to measurable functional improvements