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The pKa, which describes the dissociation of the neutral form to the negatively charged form, of sulfadiazine is 6.5 17 , making the dissociation of sulfadiazine relevant in the environment, where even slight pH changes in the vicinity of the pKa will have a major impact on the balance between the neutral and ionized fractions (Fig

doi: 10.15698/cst2019.11.203 249 ZrzavyT.HftbergerR.BergerT.RauschkaH.ButovskyO.WeinerH.et al

Since its discovery in 1973, GHK-Cu established itself as a powerful protective and regenerative ingredient, which is currently widely used in skin and hair products [0]

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