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Intratumoral talimogene laherparepvec injection with concurrent preoperative radiation in patients with locally advanced soft-tissue sarcoma of the trunk and extremities: phase IB/II trial

Dnmt and tet activity assays The Dnmt activity and Tet activity assays were conducted using a Dnmt activity/inhibition assay kit (Epigentek, Farmingdale, NY) and a Tet activity/inhibition direct assay kit (Epigentek, Farmingdale, NY), respectively, following the manufacturers protocols