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therefore, a disruption of cysteine uptake, either genetically or chemically, efficiently depletes GSH intracellular levels (42)

Acknowledgements This work was supported by grants from the National Key Research and Development Project (Grant No

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Multiple mechanisms have been studied and proven for vitamin A, including more than gene signaling pathways in terms of anticancer effects (70), the effect of retinoids on mitochondrial functions (71), and other mechanisms and pathways that have been studied and proven (72, 73)