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TSA revealed no difference in the EQ-index regarding OAC intake (observations = 1,734, n = 747

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According to an electroencephalogram/event-related potential (EEG/ERP) mapping study, in patients with multi-infarct dementia and Alzheimers disease, nicergoline improved alertness and information processing at the neurophysiological level, which led to clinical improvement at the behavioral level in both degenerative and vascular dementia [72]

Repletion of vitamin B12 may improve response in patients resistant to antidepressants (10) , and in older adults with major depression, long-term supplementation with a combination of B12, B6, and folic acid enhanced antidepressant treatment efficacy (40)