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NNMT is upregulated in the white adipose tissue of obese animals and humans, and its activity is mechanistically linked to depleted cellular NAD+ and SAM pools

is essential for mitochondrial energy production, DNA repair, and numerous enzymatic reactions, researchers have investigated how modulation of NNMT activity may influence cellular bioenergetics and metabolic efficiency

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If Youve Reached Your Goal Weight Instead of stopping suddenly, many people transition to a maintenance dose to prevent weight regain